PAR-25-221
Population Approaches to Reducing Alcohol-related Cancer Risk (R01 Clinical Trial Optional)
Summary
PAR-25-221: Population Approaches to Reducing Alcohol-related Cancer Risk
Research Focus
This funding opportunity supports interdisciplinary, population-level research on reducing alcohol-related cancer risk through awareness-building, social norm change, policy development, and intervention implementation. Alcohol consumption is a leading modifiable cancer risk factor, accounting for nearly 19,000 cancer deaths and over 75,000 cancer cases annually in the United States, with established links to oral cavity, pharynx, larynx, esophagus, colorectal, liver, and breast cancers. The program prioritizes research addressing multiple consumption levels (light, moderate, and heavy drinking) and alcohol use disorder (AUD) from a cancer prevention and control perspective. Key research gaps include low public awareness of alcohol-cancer links, conflicting health messaging, and insufficient multilevel and policy-based approaches compared to individual-level interventions. Studies should employ interdisciplinary methods across interpersonal, health system, community/organizational, and policy levels, with particular attention to underrepresented minority populations (American Indian and Alaskan Native communities) experiencing disproportionate cancer and alcohol-related disparities.
At a Glance
- Who can apply: Not stated (see NIH R01 eligibility guidelines)
- Funding & project length: Not stated
- Award mechanism: R01 Clinical Trial Optional (Research Project Grant)
- Key dates: Open January 5, 2025; multiple submission deadlines through January 8, 2027 (earliest start dates range December 2025–July 2027)
- Best fit for: Public health, cancer prevention, behavioral science, and health policy researchers using communication research, policy evaluation, and population-based intervention approaches with focus on alcohol and cancer control
Key Facts
Deadline
Thu, January 7, 2027
Posted
Wed, November 6, 2024
Award / Year (direct costs)
$250,000
Max Total
$1,250,000
Max Duration
5 years
Keywords
Research Areas
Gotchas (3)
The FOA requires 'attention to underrepresented minority and thoughtful justification of the selected target populations are important' but does not specify whether this is mandatory for all applicati
75%
Source Text
“Additionally, demographic groups, such as American Indian, and Alaskan Native populations experience cancer and alcohol-related disparities. Thus, attention to underrepresented minority and thoughtful justification of the selected target populations are important.”
The FOA distinguishes between 'population-level approaches' (which are required) and 'individual level behavioral interventions' (which are explicitly excluded). However, the boundary between these ca
80%
Source Text
“Population-level approaches involve communication, policy evaluation, and other research efforts distinct from the development of individual level behavioral interventions. Proposed studies may focus on the interpersonal, health system, community/organizational, and/or policy level and should address knowledge, social norms, and/or levels of alcohol consumption or other critical factors related to alcohol consumption for cancer control.”
The FOA was 'updated to align with agency priorities' with a notice to 'carefully reread the full funding opportunity and make any needed adjustments'—this suggests substantive changes from the prior
75%
Source Text
“This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.”