The Adolescent Brain Cognitive Development (ABCD) Study is the largest longitudinal study of brain development and child health collecting data from more than 11,000 children across the U.S. beginning when they are 9-10 years old and continuing for a decade. In addition to behavioral assessments, youth undergo neuroimaging and provide biospecimens, including saliva for hormone analysis, urine and hair for substance use and exposure, deciduous teeth for environmental exposure, and blood for genetic analysis and metabolic and hematologic assays. This initiative allows investigators to apply for access to biological samples from the ABCD Study. More information about the ABCD Study may be found on the ABCD Study website (www.abcdstudy.org). Information about this resource can be found on the NIDA funding opportunities page at https://nida.nih.gov/funding/nida-funding-opportunities/nih-brain-development-cohorts-biospecimen-access-program.

PAR-23-229: NIH Brain Development Cohorts (NBDC) Biospecimen Access (X01 Clinical Trial Not Allowed)

March 31, 2025 This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.

Department of Health and Human Services

Part 1. Overview Information

Participating Organization(s)

• National Institutes of Health (NIH)

Components of Participating Organizations

• National Institute on Drug Abuse (NIDA)
• National Institute on Alcohol Abuse and Alcoholism (NIAAA)
• National Institute of Environmental Health Sciences (NIEHS)
• National Institute of Mental Health (NIMH)
• National Institute on Minority Health and Health Disparities (NIMHD)
• National Cancer Institute (NCI)

All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.

• Office of Behavioral and Social Sciences Research (OBSSR)
• Office of Research on Women's Health (ORWH)

Funding Opportunity Title

NIH Brain Development Cohorts (NBDC) Biospecimen Access (X01 Clinical Trial Not Allowed)

Activity Code

X01 - Resource Access Award

Announcement Type

New

Related Notices

• March 31, 2025 - This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.
• April 04, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice NOT-OD-24-084
• August 31, 2022 - Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
• August 5, 2022 - Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.
• March 15, 2022 - Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R01-Clinical Trial Not Allowed) See NOFO PAR-22-137.
• March 15, 2022 - Accelerating the Pace of Child Health Research Using Existing Data from the Adolescent Brain Cognitive Development (ABCD) Study (R21-Clinical Trial Not Allowed) See NOFO PAR-22-138.
• January 10, 2022 - Accelerating the Pace of Drug Abuse Research Using Existing Data (R01 Clinical Trial Optional) See NOFO RFA-DA-22-037.
• January 10, 2022 - Accelerating the Pace of Drug Abuse Research Using Existing Data (R21 Clinical Trial Optional) See NOFO RFA-DA-22-038.

Notice of Funding Opportunity (NOFO) Number

PAR-23-229

Companion Funding Opportunity

None

Number of Applications

See Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s)

93.279, 93.307, 93.242, 93.113, 93.313, 93.273, 93.399

Funding Opportunity Purpose

The Adolescent Brain Cognitive Development℠ (ABCD) Study is the largest longitudinal study of brain development and child health in the U.S., collecting data from more than 11,000 children across the country beginning when they were 9-10 years old and continuing for a decade. In addition to behavioral assessments, youth undergo neuroimaging and provide biospecimens, including oral fluids for hormone analysis, urine and hair for substance use and exposure, deciduous teeth for environmental exposures, and blood for genetic analysis and metabolic and hematologic assays.

This initiative allows investigators to apply for access to biological samples from the ABCD Study. More information about the ABCD Study can be found on the NIDA ABCD Study web page.

Additional information about this resource is available on the NIDA funding opportunities page, under Supplemental Information for NOFOs. ABCD Study biospecimens are managed through the NIH Brain Development Cohorts (NBDC) Biorepository and Analysis Center, which offers a web portal with services related to biospecimen access. Visit the NBDC portal to query available samples using the Biospecimen Explorer, submit a Biospecimen Availability Inquiry to determine the resource availability and impact on existing samples, and learn more about this resource.

Key Dates

| |