Urgent Competitive Revisions for Public Health Crises

The National Institute of General Medical Sciences (NIGMS) is preparing a Notice of Funding Opportunity to support competitive revisions of active grants that must pivot to address unforeseen public health emergencies. This mechanism allows researchers with ongoing NIH support to redirect their work toward urgent, crisis-driven scientific needs that could not have been anticipated in the original grant proposal.

The program targets researchers whose existing projects can be meaningfully reoriented to tackle time-sensitive public health threats. Eligible revisions should demonstrate how current infrastructure, personnel, or methodological expertise can be rapidly deployed to generate evidence, tools, or interventions addressing the crisis. The intended outcome is accelerated scientific response to emergencies through existing research capacity rather than de novo project initiation.

• Who can apply: Only researchers with active NIGMS grants who receive an Urgent Guide Notice from the Institute; applications must be submitted in direct response to that Notice.
• Funding & project length: Not stated.
• Award mechanism: Competitive revision of ongoing grant.
• Key dates: NOFO publication date not yet announced; applications routed to the awarding IC upon issuance.
• Best fit for: Established researchers in any NIGMS-supported field (molecular biology, cell biology, computational biology, biomedical engineering, etc.) with existing grants and capacity to pivot toward emergency response.