The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

PAR-25-233: Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)

March 31, 2025

This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.

Department of Health and Human Services

Part 1. Overview Information

Participating Organization(s) National Institutes of Health (NIH)

Components of Participating Organizations

• National Cancer Institute (NCI)
• National Human Genome Research Institute (NHGRI)
• National Institute on Aging (NIA)
• National Institute on Alcohol Abuse and Alcoholism (NIAAA)
• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
• National Institute of Dental and Craniofacial Research (NIDCR)
• National Institute on Drug Abuse (NIDA)
• National Institute of Environmental Health Sciences (NIEHS)
• National Institute of Mental Health (NIMH)
• National Institute of Neurological Disorders and Stroke (NINDS)
• Fogarty International Center (FIC)
• Tribal Health Research Office (THRO)

All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.

• Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention (ODP)
• Office of Behavioral and Social Sciences Research (OBSSR)

Funding Opportunity Title Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)

Activity Code R03 Small Grant Program

Announcement Type Reissue of PAR-22-106

Related Notices See Notices of Special Interest associated with this funding opportunity

• April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice NOT-OD-24-084.
• August 31, 2022 - Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198.
• August 5, 2022 - Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189.

Funding Opportunity Number (FON) PAR-25-233

Companion Funding Opportunity

• PAR-25-144, R01 Small Research Grants
• PAR-25-143, R21 Exploratory/Developmental Grants

Number of Applications See Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s) 93.399, 93.121, 93.853, 93.866, 93.989, 93.865, 93.242, 93.279, 93.113, 93.172, 93.273, 93.310

Funding Opportunity Purpose The purpose of this Notice of Funding Opportunity (NOFO) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, sustainability, scale-up, and spread of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies (herein referred to collectively as evidence-based interventions). Studies that promote the dissemination and implementation of evidence-based interventions among relevant communities are encouraged. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. Applications that focus on re-implementation of evidence-based health services that may be disrupted amidst disasters remain relevant.

All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

Key Dates

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