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NIH
Posted

PAR-24-027

Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01)

Summary

AI-generated

PAR-24-027: PATH Study Biospecimen Access (X01)

Research Focus

This funding opportunity provides access to biospecimens and longitudinal data from the Population Assessment of Tobacco and Health (PATH) Study, a national cohort study designed to generate epidemiologic evidence on tobacco use behaviors, exposures, and health outcomes. The PATH Study is a collaboration between the National Institute on Drug Abuse (NIDA), NIH, and the FDA's Center for Tobacco Products (CTP), launched in 2011 to inform FDA regulatory activities under the Family Smoking Prevention and Tobacco Control Act.

Researchers can access stored biospecimens (urine, serum, plasma, and genomic DNA) collected from approximately 46,000 participants—including youth (12–17 years), adults (18+ years), and diverse tobacco product users, former users, and non-users—across four annual waves (2013–2017) and three biennial waves (2018–2023). Questionnaire data include tobacco use behaviors, addiction and cessation patterns, exposures, attitudes, beliefs, and health status. Studies addressing tobacco regulatory science priorities or expanding knowledge of tobacco use and related health outcomes are prioritized; exploratory and pilot studies are eligible.

At a Glance

  • Who can apply: Higher education institutions, nonprofits, for-profit organizations, government agencies, tribal governments, faith-based organizations, and other U.S. entities. Foreign institutions are not eligible.
  • Funding & project length: No funds awarded; mechanism provides access to biospecimens and data. Maximum project period 5 years.
  • Award mechanism: X01 Resource Access Award (not a grant or cooperative agreement).
  • Key dates: Applications due April 30, July 31, October 31, 2024 and rolling quarterly thereafter through October 30, 2026. Applicants must contact PATH Study team at least 5 months before submission to confirm biospecimen availability.
  • Best fit for: Tobacco regulatory science, epidemiology, biomarker research, and public health studies using longitudinal cohort data and biospecimen analysis in diverse U.S. populations.

Key Facts

Deadline

Fri, October 30, 2026

Posted

Thu, August 24, 2023

Max Duration

5 years

Keywords

tobacco use
biomarkers of tobacco exposure
longitudinal cohort study
electronic nicotine delivery systems
tobacco regulatory science
youth tobacco use
genomic DNA
health outcomes
tobacco product users
nicotine addiction

Research Areas

MeSH
DiseasesC
InfectionsC01Nutritional & Metabolic DiseasesC18Endocrine System DiseasesC19Immune System DiseasesC20Pathological Conditions & SymptomsC23
Chemicals & DrugsD
Organic ChemicalsD02Macromolecular SubstancesD05Amino Acids, Peptides & ProteinsD12Nucleic Acids & NucleotidesD13Complex MixturesD20Biological FactorsD23Pharmaceutical PreparationsD26
Analytical/Diagnostic/Therapeutic TechniquesE
DiagnosisE01Investigative TechniquesE05
Phenomena & ProcessesG
MetabolismG03Genetic PhenomenaG05Immune System PhenomenaG12
Disciplines & OccupationsH
Health OccupationsH02
Anthropology/Education/SociologyIInformation ScienceL
Health CareN
Population CharacteristicsN01Health Care ServicesN02Health Care Quality & EvaluationN05Environment & Public HealthN06
ANZSRC FoR
Biological Sciences31
Genetics3105Microbiology3107
Biomedical & Clinical Sciences32
Immunology3204Medical Biochemistry & Metabolomics3205
Health Sciences42
Epidemiology4202Public Health4206
Information & Computing46
Data Management & Data Science4605
Mathematical Sciences49
Statistics4905

Gotchas (3)

Soft Block
writingsubmission documentation

Applicants must contact the PATH Study team at least five months in advance of application submission deadlines to confirm biospecimen availability and obtain written confirmation before submitting an

AI

95%

Source Text

Interested applicants are required to contact the PATH Study team at least five months in advance of the application submission deadlines to determine whether there is sufficient quantity of the biospecimens required for the proposed study. Applications must include written confirmation from the PATH Study team indicating sufficient numbers of biospecimens.

Warning
planningbudget period duration

The maximum project period is 5 years, which is a constraint on award duration that applicants must respect in project planning.

AI

85%

Source Text

Award Project Period: The scope of the proposed project should determine the project period. The maximum project period is 5 years.

Warning
planningprogram scope topic

Studies addressing PATH Study objectives and tobacco regulatory science research priorities receive highest priority; other studies expanding knowledge of tobacco use receive lower priority. This crea

AI

90%

Source Text

Investigators proposing meritorious and feasible studies including exploratory or pilot studies, consistent with PATH Study objectives and/or research priorities for tobacco regulatory science will be given the highest priority for access to PATH Study biospecimens. Studies that address other objectives that expand the knowledge of tobacco use and/or tobacco related health outcomes will also be considered but will be a lower priority.

AI-generated content — verify with the issuing agency’s official FOA/NOFO. Not endorsed by HHS.

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