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NIH
Posted

RFA-AG-26-011

NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed)

Summary

AI-generated

NIA Expanding Research in AD/ADRD Summer Research Education Program (R25)

Research Focus & Contribution

This program supports summer research education experiences designed to expand and diversify the Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD) research workforce. The NIA seeks to address a critical shortage of scientists in AD/ADRD research—spanning basic biomedical, behavioral, clinical, translational, prevention, and treatment domains—by providing early-stage exposure to hands-on research. Programs target high school students, undergraduates, or science teachers with intensive 8–14 week summer experiences that combine authentic, open-ended laboratory work with complementary educational enrichment (scientific writing, presentation skills, journal clubs, technical coursework). The intended contribution is twofold: to incubate the next generation of early-career investigators in NIA mission-critical areas including frontotemporal dementia, Lewy body dementia, and vascular dementia, and to strengthen STEM retention and interest in aging-related research among younger populations. Participants may gain research experience in clinical trials led by mentors, though they cannot lead independent trials.

At-a-Glance

  • Who can apply: Academic institutions (R25 education grants); programs must be distinct from existing federally-funded training and cannot replace NRSA programs.
  • Funding & project length: Up to $200,000 direct costs per year for a 5-year project period; 8–14 weeks of summer research education annually.
  • Award / mechanism: R25 Education Projects grant; up to 5 new awards per year in FY 2027 and FY 2028 ($1,000,000 total commitment each year).
  • Key dates: Applications open April 27, 2026; earliest start date May 27, 2026; expiration May 27, 2027.
  • Best fit for: Institutions with AD/ADRD research capacity seeking to develop summer pipelines for high school students, undergraduates, or STEM teachers; programs emphasizing dementia subtypes, aging neurobiology, and translational research pathways.

Key Facts

Deadline

Wed, May 26, 2027

Posted

Tue, September 2, 2025

Award / Year (direct costs)

$200,000

Max Total

$1,000,000

Max Duration

5 years

93.866
Detailed
Grants.gov
Agency

Keywords

Alzheimer's Disease
frontotemporal dementia
Lewy body dementia
vascular dementia
brain health
aging research
translational research
behavioral research
biomedical research
STEM education
summer research programs
clinical research
Alzheimer's disease-related dementias
neurodegenerative diseases
research workforce development

Research Areas

MeSH
DiseasesC
Nervous System DiseasesC10Endocrine System DiseasesC19Pathological Conditions & SymptomsC23
Analytical/Diagnostic/Therapeutic TechniquesE
DiagnosisE01TherapeuticsE02
Phenomena & ProcessesG
Genetic PhenomenaG05
Disciplines & OccupationsH
Natural Science DisciplinesH01Health OccupationsH02
Anthropology/Education/SociologyI
EducationI02Human ActivitiesI03
Health CareN
Health Care ServicesN02Health Care EconomicsN03Health Care Quality & EvaluationN05
ANZSRC FoR
Biomedical & Clinical Sciences32
Clinical Sciences3202Neurosciences3209
Education39
Curriculum & Pedagogy3901Education Policy & Philosophy3902Specialist Studies in Education3904
Health Sciences42
Health Services & Systems4203Public Health4206
Human Society44
Mathematical Sciences49
Statistics4905

Gotchas (4)

Soft Block
discoverymeta ambiguity

Programs must be 'distinct from those training and education programs currently receiving federal support' and cannot 'replace or circumvent' NRSA programs, but the criteria for determining distinctne

AI

90%

Source Text

Research education programs may complement ongoing research training and education occurring at the applicant institution, but the proposed educational experiences must be distinct from those training and education programs currently receiving federal support. R25 programs may augment institutional research training programs (e.g., T32, T90), but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs.

Warning
planningprogram clinical trial

Participants cannot lead an independent clinical trial, but may participate in clinical trials led by mentors—this distinction could be misunderstood as a blanket prohibition on clinical trial involve

AI

85%

Source Text

This NOFO does not allow participants to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Warning
planningprogram required components

Applicants must demonstrate that the program 'will add significant value over existing programs at the applicant institution,' but no criteria or examples are provided for what constitutes 'significan

AI

80%

Source Text

Applicants must demonstrate how this program will add significant value over existing programs at the applicant institution.

Warning
planningbudget cost allowability

Science teacher participant compensation is capped at $20,000 per teacher, but the FOA does not clarify whether this is an annual cap or a total cap for the entire project period.

AI

75%

Source Text

Science teachers can be provided with salary and fringe benefits up to $20,000 per science teacher.

AI-generated content — verify with the issuing agency’s official FOA/NOFO. Not endorsed by HHS.

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