PAR-25-091
Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
Summary
PAR-25-091: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients
Research Focus
This program supports researchers transitioning to independent investigator status by providing supplemental R03 Small Grant funding to current NIDDK-supported mentored career development award (K01, K08, K23, K25) recipients. The R03 mechanism funds pilot and feasibility studies, secondary data analysis, small self-contained research projects, development of research methodology, and new research technology—all within NIDDK's mission interests (diabetes, digestive diseases, kidney disease, and related metabolic disorders). The goal is to enable K recipients to expand current research objectives or pursue closely related pilot work, generating preliminary data and publications to support transition to R01 or equivalent independent research grants. Applications proposing clinical trials are optional.
At a Glance
- Who can apply: Current NIDDK K01/K08/K23/K25 recipients only; ineligible if already holding an R01 or equivalent grant; one award per applicant.
- Funding & project length: $75,000 direct costs per year, maximum 2-year project period.
- Award mechanism: R03 Small Grant (limited competition).
- Key dates: Applications due February 16, 2025 (earliest); subsequent rounds June 16, October 16, 2026, and beyond. Earliest start date December 2025.
- Best fit for: Diabetes, digestive disease, kidney disease, and metabolic research; investigators seeking pilot data, methodology development, or secondary analyses to bridge K-award completion and R01 competitiveness.
Key Facts
Deadline
Fri, January 7, 2028
Posted
Fri, January 10, 2025
Award / Year (direct costs)
$75,000
Max Total
$150,000
Max Duration
2 years
Keywords
Research Areas
Gotchas (3)
Applicants may only receive one award under this program. This is a strict one-award-per-PI limit that differs from typical NIH mechanisms and could disqualify resubmissions or multiple applications f
90%
Source Text
“Additionally, individuals are only eligible to received one award under this program.”
Only current NIDDK K01/K08/K23/K25 recipients are eligible; K recipients who have already successfully competed for an R01 or equivalent grant are ineligible. This is a strict eligibility gate that co
95%
Source Text
“Only current NIDDK-supported K01, K08, K23, or K25 recipients are eligible to apply for this funding opportunity. K-recipients who have already successfully competed for an R01, or equivalent, grant are ineligible. See this website for the definition of 'equivalent' R01 grant.”
Applications must propose projects within NIDDK's mission interests. Non-responsive applications will not be reviewed. This is a pre-review screen that could result in desk rejection if the project sc
85%
Source Text
“While applications for the R03 program do not necessarily need to be directly related to the ongoing K award, they must propose projects within the mission interests of the NIDDK. Applications that propose projects outside of NIDDK's research mission interests will be considered non-responsive. Non-responsive applications will not be reviewed.”