SPF-PFS States Program

Research Focus

The SPF-PFS States program funds community-based substance use prevention services designed to interrupt the initiation and progression of substance use disorders. The program emphasizes a protective factors framework—strengthening community and individual resilience while reducing established risk factors—rather than solely targeting high-risk populations. Funded work spans prevention strategy implementation across diverse settings (schools, community organizations, tribal nations) and includes capacity-building for prevention providers to deliver evidence-based, evidence-informed, and community-defined prevention interventions. The intended contribution is measurable reduction in substance use initiation and related harms through sustained, culturally adapted prevention delivery at scale.

At a Glance

• Who can apply: States and federally recognized tribes; applicants must demonstrate capacity to serve communities and tribes (critical: tribal consultation/partnership required for work affecting tribal populations)
• Funding & project length: Not stated
• Award / mechanism: Cooperative agreement (capacity-building + service delivery support)
• Key dates: Not stated
• Best fit for: Public health, prevention science, and community health researchers with experience in substance use prevention, health equity, and implementation science in community or tribal settings