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NIH
Forecasted

NOT-DK-26-312

Notice of Intent to Publish a Funding Opportunity Announcement for Single Source for Continuation of the Environmental Determinants of Diabetes in The Young Study (TEDDY) Data Coordinating Center (U01 Clinical Trial Not Allowed)

Summary

AI-generated

Briefing: TEDDY Study Data Coordinating Center Support

This is a non-competitive, single-award funding opportunity from the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK) to support continuation of the Data Coordinating Center (DCC) for The Environmental Determinants of Diabetes in the Young (TEDDY) study. TEDDY is an ongoing epidemiological cohort study investigating environmental and genetic factors that trigger type 1 diabetes in children. The DCC, based at University of South Florida, has managed study design, data collection, and biosampling since the consortium's inception and is currently conducting a second case-control analysis of the TEDDY cohort. This funding will enable completion of ongoing analyses from the second case-control cohort and support study closeout activities. The work spans data management, epidemiological analysis, and pediatric diabetes prevention research, contributing to the Special Diabetes Program's mission to advance prevention, treatment, and cure strategies for type 1 diabetes and its complications.

  • Who can apply: University of South Florida only (non-competitive, single-award mechanism restricted to USF as the designated DCC).
  • Funding & project length: Not stated.
  • Award mechanism: Cooperative agreement (UH3).
  • Key dates: Not stated.
  • Best fit for: Epidemiological data management and case-control analysis in pediatric type 1 diabetes research; cohort-based biostatistics and environmental risk factor investigation.

Insights (5)

Single-Award Non-Competitive Mechanism Restricts Applicant Pool to USF Only

eligibility

This is explicitly a non-competitive, single-source cooperative agreement restricted to University of South Florida as the incumbent Data Coordinating Center for TEDDY. No other institution can apply, regardless of qualifications or research strength. This is not a competitive opportunity for external researchers.

Continuation Funding Requires Demonstrated DCC Leadership and Cohort Continuity

strategic fit

USF's competitive advantage rests entirely on institutional history: inception-to-present involvement in TEDDY study design, data/biosample management, and initiation of the second case-control analysis. Applicants must demonstrate seamless operational continuity and analytical progress on the ongoing case-control cohort to justify renewal.

DCC Role Emphasizes Data Management and Operations Over Novel Discovery

career stage

This mechanism funds completion of existing analyses and study closeout rather than hypothesis-driven research innovation. Career advancement depends on demonstrating rigorous data stewardship, analytical execution, and consortium leadership—not novel methodological or scientific breakthroughs. Suitable for researchers with strong operational and biostatistical portfolios.

TEDDY Consortium Membership and Multi-Site Coordination Are Structural Requirements

collaboration

As the DCC, USF must coordinate across the TEDDY Consortium's multiple clinical sites and manage complex multi-site data and biosamples. Success requires established relationships, governance structures, and operational protocols with consortium partners. This is not a standalone research award.

No Competition; Funding Certainty Contingent on Acceptable Performance and Scope

competition

With only one award available and restricted to USF, there is no peer competition. However, funding is contingent on demonstrating acceptable progress on case-control analysis completion and study closeout. Scope creep or analytical delays could jeopardize renewal.

Key Facts

Deadline

Posted

Mon, May 12, 2025

Award Range

$6,000,000

Expected Awards

1

UH3
93.855
Grants.gov

Keywords

type 1 diabetes
epidemiological study
data coordinating center
diabetes prevention
environmental determinants
cohort study
data management
case-control analysis
pediatric diabetes

Research Areas

NIH Institute
Allergy & Infectious DiseasesNIAID
OpenAlex
Life SciencesD1Health SciencesD4
Fields
Agricultural & Biological SciencesF11Immunology & MicrobiologyF24MedicineF27Pharmacology, Toxicology & PharmaceuticsF30
Subfields
Endocrinology, Diabetes & MetabolismS2712EpidemiologyS2713Genetics (Medical)S2716Health InformaticsS2718Public Health & Occupational HealthS2739
Topics
Genetic Associations and EpidemiologyT10261Diabetes Treatment and ManagementT10401Mathematical and Theoretical Epidemiology and Ecology ModelsT10482Diabetes Management and ResearchT10560Diabetes and associated disordersT11171Health and Medical Research ImpactsT12168Chronic Disease Management StrategiesT12246Medical and Health Sciences ResearchT13275
MeSH
DiseasesC
Nutritional & Metabolic DiseasesC18Endocrine System DiseasesC19Immune System DiseasesC20
Analytical/Diagnostic/Therapeutic TechniquesE
DiagnosisE01Investigative TechniquesE05
Phenomena & ProcessesG
MetabolismG03
Disciplines & OccupationsH
Health CareN
Health Care ServicesN02Health Care EconomicsN03Health Services AdministrationN04Health Care Quality & EvaluationN05Environment & Public HealthN06
ANZSRC FoR
Biomedical & Clinical Sciences32
Medical Biochemistry & Metabolomics3205Oncology & Carcinogenesis3211
Health Sciences42
Epidemiology4202Public Health4206
Mathematical Sciences49
Statistics4905

Gotchas (1)

Soft Block
eligibilityeligibility applicant organization

This is a non-competitive, single-award funding opportunity restricted to University of South Florida as the Data Coordinating Center for the TEDDY study. Only USF is eligible to apply.

AI

99%

Source Text

This is a non-competitive funding opportunity intended to fund a single award. The National Institute of Diabetes and Digestive and Kidney Disease (NIDDK) is announcing its intent to issue a single source cooperative agreement award to University of South Florida for of the current Data Coordinating Center (DCC) for The Environmental Determinants of Diabetes in the Young (TEDDY) study

AI-generated content — verify with the issuing agency’s official FOA/NOFO. Not endorsed by HHS.

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