PAR-23-126
Limited Competition: National Primate Research Centers (P51) (Clinical Trials Not Allowed)
Summary
PAR-23-126: National Primate Research Centers (P51)
Research Focus
This program funds the National Primate Research Centers (NPRCs), centralized facilities that provide nonhuman primates (NHPs), specialized expertise, and infrastructure to enable biomedical and behavioral research. Because NHPs are physiologically and genetically closest to humans, they serve as critical animal models for understanding human biology in normal and diseased states. The NPRCs support basic and translational research across multiple disease areas and health conditions, with emphasis on developing and validating NHP disease models, enhancing research rigor and reproducibility, breeding and characterizing genetically defined and pathogen-free animals, and conducting pilot biomedical projects. Centers also provide normative data, biologic and genetic materials, consultative expertise, and training opportunities in primatology to advance the scientific utility and well-being of research animals.
At a Glance
- Who can apply: Existing National Primate Research Centers only (limited competition); applicants must be affiliated with a major research institution.
- Funding & project length: Not stated; P51 base grant amount not specified in this excerpt.
- Award mechanism: P51 (Primate Research Center Grant); multi-project grant structure.
- Key dates: Application due dates on rolling schedule (September 25, 2023 onwards, quarterly); expiration September 26, 2026.
- Best fit for: Established primate research centers conducting NHP-based research in disease modeling, colony management, genetic characterization, and translational science; clinical trials not allowed.
Note: Specific funding amounts, project duration, and detailed eligibility criteria are not provided in this excerpt. Consult the full FOA and institutional contacts for complete budget and timeline information.
Key Facts
Deadline
Fri, September 25, 2026
Posted
Fri, May 26, 2023
Max Duration
5 years
Keywords
Research Areas
Gotchas (4)
This FOA is explicitly limited to existing NPRCs only; new applicants cannot apply even if they meet all other criteria
99%
Source Text
“Applicants to this FOA are limited to existing NPRCs.”
Clinical trials are explicitly prohibited in this P51 mechanism, which is unusual and must be strictly observed
99%
Source Text
“Limited Competition: National Primate Research Centers (P51) (Clinical Trials Not Allowed)”
The Center Director must have a doctoral degree in health sciences and proven track record of scientific leadership on NHP research specifically; this is a stricter requirement than typical NIH leader
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Source Text
“The Center Director must be an established scientist with a doctoral degree in one of the health sciences disciplines and must have a proven track record of scientific leadership related to NHP research (e.g., PI on peer-reviewed research grants and/or development and leadership of high-impact team science initiatives).”
The P51 base grant is explicitly stated as NOT intended to provide total NPRC funding; centers must secure substantial augmentation from other sources (program income, peer-reviewed grants, contracts)
95%
Source Text
“The P51 base grant is not intended to provide the total funding for the NPRC. Funding of NPRC operations should be augmented by other sources such as program income, peer-reviewed research grants, contracts, or cooperative agreements and other sources, as appropriate.”